Thio-2
Unsuitables - unsuitable to be used as a chemical probe
Structure
This is unsuitable as a chemical probe: While this
compound has been used to interrogate specific protein
targets, it is not a chemical probe and should not be used
in assays that depend on a potent and selective modulator
of the protein.
Non selective compound
Intended target=BAG1-HSC70 interaction; this class of molecules exhibits multiple off-target activities including CYP1A1-mediated generation of reactive intermediates and DNA adducts (PMID: 20670034).